HOW DOES RELAPSING MS CHANGE OVER TIME?
When you have RMS, your immune system mistakenly attacks the nerves in your central nervous system (CNS), causing inflammation and relapses.

As RMS progresses, inflammation in the brain lessens as nerve damage in the brain and spinal cord (neurodegeneration) increases. This shift is what causes your RMS to feel different. And it's why you may experience new or worsening symptoms.


WATCH
& LEARN
Get a deeper look at the changing
nature of RMS from an MS expert
in this video.
HOW IS DISABILITY PROGRESSION MEASURED?
The Expanded Disability Status Scale (EDSS)
is commonly used in clinical trials to measure
the combined effects of physical and cognitive disability,
and track progression over time.
Your EDSS score is determined by how you function in 8 key functional areas, and can
range from 0 to 10. The higher your EDSS score, the greater
your level of disability.
KEY AREAS OF FOCUS FOR
DETERMINING DISABILITY
KEY AREAS OF FOCUS FOR DETERMINING DISABILITY


Assistance
required to walk
Assistance
required to walk

Weakness or
problems moving limbs

Trouble with
memory or
concentration

Problems with coordination

Weakness or
problems moving
limbs

Bowel and
bladder issues

Vision
problems

Trouble with
memory or
concentration

Problems with
coordination

Vision problems

Difficulty with
speech or
swallowing

Difficulty with
speech or
swallowing

Bowel and
bladder issues


Numbness
or loss of
sensation
Numbness or loss
of sensation
DISABILITY PROGRESSION OVER TIME

To measure the changes in disability during clinical trials, doctors commonly use confirmed disability progression (CDP). Any change in disability that remains consistent over a certain period of time, such as 3 months, is considered CDP.*
*CDP is not the only measure for disease progression.
HOW CAN I TELL IF MY RELAPSING MS IS PROGRESSING?

You may have fewer relapses and may not be fully bouncing back or recovering in between them

The number of active lesions appearing on your MRI may decrease

You may have trouble walking or are relying more on a walking aid

BOOK A
VIRTUAL
VISIT
If your RMS is starting to feel
different,
have a live conversation
with a neurologist from your
computer, tablet, or smart phone.
WHAT DOES THIS MEAN FOR ME?
Even a small increase in your disability can have an impact and interrupt the balance between your mind and body. Answer a few questions about your changing RMS and its impact to create a personalized conversation guide. Share it with your doctor to see if once-daily MAYZENT® may be right for you.

TRACK RMS SYMPTOMS
Create a personalized discussion guide to help you talk to your doctor about relapsing MS progression and MAYZENT.
SHARE THIS SITE WITH YOUR
DOCTOR TO LET THEM KNOW
YOU WOULD LIKE TO DISCUSS
MAYZENT AT YOUR NEXT VISIT
THANKS!
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